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Excellent review articles on North American blastomycosis are available.

Although high-frequency low-intensity transcutaneous electric nerve stimulation (TENS) has been extensively used to relieve low back pain, experimental studies of its effectiveness have yielded contradictory findings mainly due to methodological problems in pain evaluation and placebo control.

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During the last two decades, however, a clearer picture of the disease process has emerged, particularly as a result of studies by the Duke Medical School group, headed by Smith, Martin, and Conant.

Numerous clinical and laboratory reports have contributed significantly to a fuller understanding of the disease, but there are still some fundamental question to be answered.

In order to measure the short-term effect of TENS, VAS pain ratings were taken before and after each treatment session.

Also, to measure long-term effects, patients rated their pain at home every 2 h throughout a 3-day period before and 1 week, 3 months and 6 months after the treatment sessions.

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